Treatment of Nodular Cystic Acne with Accutane

Accutane is a medication used to treat severe nodulo-cystic acne that has failed to improve with other treatments, including oral antibiotics. It is a powerful medicine with potentially serious side effects.

Accutane could result in serious complications if you have one of the following medical conditions:

Depression
Diabetes
High blood lipids
Liver disease
Alcohol abuse problem
Breast-feeding or pregnancy
Inflammatory bowel disease (ulcerative colitis & Crohn's disease)
Unusual or allergic reaction to isotretinoin, retinoids, parabens, dyes, or preservatives.

Accutane has been associated with a condition called "pseudotumor cerebri" (increased pressure in the brain) - a serious complication. In addition, it could cause interactions with certain medicines, vitamins, alcohol, or illegal drugs. There are many other side effects associated with the use of Accutane; you need to discuss this with your doctor if you are considering this medication.

Severe birth defects have occurred in babies of women who took Accutane during pregnancy. Consequently, if you are a woman taking Accutane, you must use two forms of reliable birth control simultaneously even if you think you cannot become pregnant, unless you abstain from sexual intercourse or have had a hysterectomy. Since pregnancy while on Accutane is a serious concern, you must wait until the second or third day of your next normal menstrual period before starting Accutane.

Because of the many potentially serious complications associated with Accutane's use, your physician will need to follow your progress very closely if you are started on Accutane. This involves monthly (or more frequent) checks, including physical exam, blood and/or urine tests, and monthly pregnancy tests for women.

Before considering Accutane you need to look at several factors:

The physician should decide independently (after a thorough medical history and physical exam) if you are an appropriate candidate for Accutane. Sometimes, the physician may conclude that you are not an appropriate candidate for Accutane.

Women should anticipate starting Accutane on the second or third day of their menstrual cycle, and plan their appointments accordingly.

Accutane is expensive.

Treatment lasts four to five months.

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